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Most specific biochemical reactions depend on molecules fitting closely together. This is why optical isomers are usually inactive, and why the key classes of molecules, such as the nucleic acids and the proteins, occur only in one hand. So to study function you must study the exact shape of biological molecules and their changes in shape. - Francis Crick, 2002
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Contact Information |
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Structural Biology Laboratory |
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Recent Publications
Oct 28
Mario Kuo, Innokentiy Maslennikov, Brent Molden, Senyon Choe (2008) The desensitization gating of the MthK K channel is governed by its cytoplasmic amino terminus. PLoS Biol. 6, e223. Aug 5 Wang, L., Maji, S.K., Sawaya, M.R., Eisenberg, D., Riek, R. (2008) Bacterial Inclusion Bodies Contain Amyloid-Like Structure. PLoS Biol. 6, e195. July 25 Rodgers, L., Gamez, A., Riek, R., Ghosh, P. (2008) The type III secretion chaperone SycE promotes a localized disorder-to-order transition in the natively unfolded effector YopE. J Biol Chem.283, 20857-63. View publication in:
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