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Most specific biochemical reactions depend on molecules fitting closely together. This is why optical isomers are usually inactive, and why the key classes of molecules, such as the nucleic acids and the proteins, occur only in one hand. So to study function you must study the exact shape of biological molecules and their changes in shape. - Francis Crick, 2002
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Contact Information |
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Structural Biology Laboratory |
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Recent Publications
Nov 1
Dvir H, Choe S. (2009) Bacterial expression of a eukaryotic membrane protein in fusion to various Mistic orthologs. Protein Expr Purif., 68, 28-33. Jul 1 Dvir H, Lundberg ME, Maji SK, Riek R, Choe S. (2009) Mistic: cellular localization, solution behavior, polymerization, and fibril formation. Protein Sci., 18, 1564-70. June 28 Aryal P, Dvir H, Choe S, Slesinger PA. (2009) A discrete alcohol pocket involved in GIRK channel activation. Nat Neurosci., 12, 988-95. View publication in:
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