Ion Channels 

Farina, A.N., Blain, K.Y., Maruo, T., Kwiatkowski, W., Choe, S., Nakagawa, T. (2011) Sepearation of domain contacts is required for heterotetrameric assembly of functional NMDA receptors. J. Neurosci. 31, 3565-79.

Balana, B., Maslennikov, I., Kwiatkowski, W., Stern, K.M., Bahima, L., Choe, S., Slesinger, P.A. (2011) Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27. Proc. Natl. Acad. Sci. 108, 5831-6.

Dvir, H., Valera, E., Choe, S. (2010) Structure of MthK RCK in complex with cadmium. J. Struct. Biol. 171, 171, 231-7.

Roosild TP, Castronovo S, Miller S, Li C, Rasmussen T, Bartlett W, Gunasekera B, Choe S, Booth IR. (2009) KTN (RCK) domains regulate K+ channels and transporters by controlling the dimer-hinge conformation. Structure. 17, 893-903.

Aryal P, Dvir H, Choe S, Slesinger PA. (2009) A discrete alcohol pocket involved in GIRK channel activation. Nat Neurosci., 12, 988-95.

Mario Kuo, Innokentiy Maslennikov, Brent Molden, Senyon Choe (2008) The desensitization gating of the MthK K channel is governed by its cytoplasmic amino terminus. PLoS Biol. 6, e223.

Baker, K.A., Tzitzilonis, C., Kwiatkowski, W., Choe, S., Riek, R. (2007) Conformational dynamics of the KcsA potassium channel governs gating properties. Nat Struct Mol Biol. 14, 1089-95.

Mario M. Kuo, Y. Saimi, C. Kung, S. Choe (2007) Patch Clamp and Phenotypic Analyses of a Prokaryotic Cyclic Nucleotide-gated K+ Channel Using Escherichia coli as a Host. J Biol Chem. 282,24294-301.

Pegan, S., Tan, J., Huang, A., Slesinger, P.A., Riek, R., Choe, S. (2007) NMR studies of interactions between C-terminal tail of Kir2.1 channel and PDZ1,2 domains of PSD95. Biochemistry. 46, 5315-22.

Kuo, M. M-C., Baker, K.A., Wong, L., Choe, S. (2007) Dynamic oligomeric conversions of the cytoplasmic RCK domains mediate MthK potassium channel activity. Proc. Natl. Acad. Sci. 104, 2151-6.

Scott Pegan, Christine Arrabit, Paul Slesinger, Senyon Choe (2006) Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1. Biochemistry 45, 8599-8606.

Kent Baker, Christian Hilty, Alisson Prince, Paul Pfaffinger, Gehard Wider, Kurt Wuthrich, Senyon Choe (2006) NMR-derived dynamic aspects of N-type inactivation of a Kv channel suggest a transient interaction with the T1 domain. Biochemistry, 45, 1663-1672.

Scott Pegan, Christine Arrabit, Wei Zhou, Witek Kwiatkowski, Anthony Collins, Paul Slesinger, Senyon Choe (2005) Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification. Nature Neuroscience 8, 279-287.

Nanao, M., Green, T., Stern-Bach, Y., Heinemann, S.F., Choe, S. (2005) Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid. Proc. Natl. Acad. Sci.102,1708-13.

Zhou, W., Qian, Y., Kunjilwar, K., Pfaffinger, P.J. and Choe S. (2004) Structural Insights into the Functional Interaction of KChIP1 with Shal-Type K+ Channels Neuron, 41, 573-586.

Roosild, T., Le, T.-K., Choe, S. (2003) Cytoplasmic gatekeepers of K channel flux: a structural perspective Trends in Biochem. Sci., 29, 39-45.

Max H. Nanao, Wei Zhou, Paul J. Pfaffinger, and Senyon Choe (2003) Determining the basis of channel-tetramerization specificity by x-ray crystallography and a sequence-comparison algorithm: Family values (FamVal) PNAS, 100, 8670-8675.

Choe, S. & Roosild, T. (2002) Regulation of K channels by cytoplasmic domains. Biopolymers, 66, 294-299.

Jahng, A., Strang, C., Kaiser, D., Pollard, T., Pfaffinger, P., Choe, S. (2002) Tetrameric assembly of T1 of Kv4.2 is Zn-dependent. J. Biol. Chem., 277, 47885-90.

Roosild, T., Miller, S., Booth, I., Choe, S. (2002) A mechanism of regulation for potassium flux mediated by conformational change. Cell, 109, 781-791.

Choe, S. (2002) Potassium Channel Structures. Nature Reviews Neurosci, 3, 115-121.

Choe, S., Cushman, S., Baker, K.A., Pfaffinger, P. (2002) Excitability is mediated by the T1 domain of the voltage-gated K channel. Novartis Foundation Symposium 245, 169-177.

Biggin, P.C., Smith, G.R., Shrivistava, I., Sansom, M.S.P., Choe, S. (2001) Properties and effects of single cations through the potassium channel, KcsA, studied by molecular dynamics simulation. B.B.A. 1510, 1-9.

Zhou, W., Arrabit, C., Choe, S., Slesinger, P. (2001) Bupivacaine inhibits ethanol- and G protein-gated inwardly rectifying potassium channels. Proc. Natl. Acad. Sci., 98, 6482-7.

Choe, S., Kreusch, A., Pfaffinger, P.J. (1999) Towards the three-dimensional structure of voltage-gated potassium channels. Trends in Biol. Sci., 24, 345-349.

Bixby, K., Nanao, M., Shen, V., Kreusch, A., Bellamy, H., Pfaffinger, P., Choe, S. (1999) Zn2+-mediated and molecular determinants of tetramerization in voltage-gated K+ channels. Nature Struc. Biol., 6, 38-43.

Kreusch, A., Pfaffinger, P., Stevens, C.F., Choe, S. (1998) Crystal structure of the tetramerization domain of the Shaker potassium channel. Nature 392, 945-8.

Choe, S., Robinson, R. (1998) An ingenious filter: the structural basis of ion selectivity. Neuron 20, 821-3.